When This Medicine Should Not Be Used:
You should not use this medicine if you have had an allergic reaction to ivermectin.

How to Use This Medicine:
Tablet

• Your doctor will tell you how much medicine to use. Do not use more than directed.
• It is best to take this medicine on an empty stomach with a full glass (8 ounces) of water.
• Usually, you will need only one dose of the medicine to treat your infection.
• However, patients with immune system disorders, such as those with human immunodeficiency virus (HIV) infection, may need to use a dose every 2 weeks for several weeks to treat the infection. Some patients may need to use the medicine every month to keep the infection from coming back.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breastfeeding.
• Tell your doctor if you are being treated for an intestinal infection from threadworms. You will need to have your bowel movements tested to make sure that the infection is gone. It is very important that you have these tests done as often as your doctor orders.
• If you are being treated for river blindness (onchocerciasis), you may need retreatment and surgery to kill the adult parasite. You will need to see your doctor for follow up care.
• Call your doctor if your symptoms do not improve or if they get worse.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Eye or eyelid irritation, pain, redness, or swelling.
• Fainting.
• Fever.
• Joint pain.
• Severe itching, rash, or hives.
• Swelling or tenderness under your arms, in your neck, or around your groin.

If you notice these less serious side effects, talk with your doctor:

• Diarrhea, nausea, vomiting, or stomach pain.
• Dizziness.
• Mild rash or itching.
• Tiredness or weakness.

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088