When This Medicine Should Not Be Used:
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to regadenoson, or if you have certain heart rhythm problems.

How to Use This Medicine:
Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
• A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some foods and medicines can affect how regadenoson works. Tell your doctor if you are using aminophylline, dipyridamole, or theophylline. You may need to stop using dipyridamole for at least 2 days before this test, and stop using aminophylline or theophylline for at least 12 hours before this test.
• Do not eat or drink anything that contains caffeine for at least 12 hours before you receive this medicine. This includes medicines, foods, and drinks with caffeine, such as coffee, tea, and cola drinks.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have asthma, chronic obstructive pulmonary disease (COPD), heart or blood vessel disease, heart valve disease, seizures, or unstable angina.
• This medicine may cause the following problems:
  
  • Serious risk of heart attack, stroke, or heart rhythm problems
  • High or low blood pressure
  • Seizures

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating
• Fast, slow, or uneven heartbeat
• Lightheadedness, dizziness, or fainting
• Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking

If you notice these less serious side effects, talk with your doctor:

• Headache
• Upset stomach
• Warmth or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088