When This Medicine Should Not Be Used:
This medicine is not right for everyone. Do not receive it if you had an allergic reaction to amphotericin B.

How to Use This Medicine:
Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
• A nurse or other health provider will give you this medicine.
• Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how amphotericin B works. Tell your doctor if you are taking any of the following:
  
  • Antibiotic medicine
  • Corticosteroid medicine, such as prednisone or cortisone
  • Digoxin
  • Diuretic medicine (water pills)
  • Other antifungal medicine

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blistering, peeling, red skin rash
• Change in how much or how often you urinate
• Dry mouth, increased thirst, muscle cramps
• Fast, slow, or uneven heartbeat
• Severe nausea and vomiting
• Shaking, fever, and chills
• Swelling of the hands, ankles, or feet
• Trouble breathing

If you notice these less serious side effects, talk with your doctor:

• Swelling, pain, or redness near where the IV needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088