When This Medicine Should Not Be Used:
You should not use this medicine if you have had an allergic reaction to meclofenamate, aspirin, or other pain and arthritis medicines such as Motrin®, Indocin®, Naprosyn® or Aleve®, Tolectin®, or Clinoril®. The reaction may have included wheezing or trouble breathing, hives, rash, or swelling in the face.

How to Use This Medicine:
Capsule

• Your doctor will tell you how much to take and how often.
• Take with a full glass of water.
• You may take the medicine with food, milk, or antacids (such as Maalox® or Mylanta®) so it does not upset your stomach.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• You should not use this medicine with aspirin, products that contain aspirin, naproxen (Aleve®) or ibuprofen (Advil®or Motrin®).
• Avoid drinking alcohol while you are taking this medicine.
• Make sure your doctor knows if you are taking Coumadin®.

Warnings While Using This Medicine:

• Talk with your doctor before taking this medicine if you are pregnant, breastfeeding, or have heart disease, high blood pressure, liver or kidney disease, blood disorders, or ulcers or other stomach problems.
• Ulcers and stomach bleeding are sometimes caused by this type of medicine. These problems can happen without warning signs. You may need to see your doctor for regular check-ups while being treated with this medicine.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Severe rash or hives
• Rapid swelling of face or around eyes
• Chest tightness or trouble breathing
• Sore throat or fever
• Unusual bleeding or bruising
• Yellowing of skin or eyes
• Decreased amount of urine
• Severe stomach pain or vomiting blood
• Black, tarry or bloody stools

If you notice these less serious side effects, talk with your doctor:

• Diarrhea
• Nausea
• Heartburn or gas
• Headache
• Dizziness
• Swelling of feet or legs or weight gain
• Ringing in the ears

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088