When This Medicine Should Not Be Used:
You should not use this medicine if you have had an allergic reaction to levorphanol.

How to Use This Medicine:
Tablet

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
• You may take this medicine with or without food.
• Drink plenty of liquids to help avoid constipation.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if are using droperidol, hydroxyzine, or phenothiazines such as prochlorperazine, Compazine®, Phenergan®, Thorazine®, or Trilafon®.
• Make sure your doctor knows if you are also using an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate®.
• Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.
• Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breast feeding, or if you have had an allergic reaction to a pain medicine in the past.
• Make sure your doctor knows if you have asthma, brain disease, gallbladder disease, heart disease, kidney disease, liver disease, or lung problems such as asthma or emphysema.
• Make sure your doctor knows if you have had a serious head injury, or any medical condition that causes increased pressure in your head.
• This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
• Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
• This medicine may make you drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
• This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Decrease in how much or how often you urinate.
• Lightheadedness or fainting.
• Severe vomiting, pain in your stomach.
• Slow heartbeat.
• Slow or shallow breathing.

If you notice these less serious side effects, talk with your doctor:

• Blurred vision.
• Bad dreams or abnormal thoughts.
• Confusion, dizziness, drowsiness, or tired feeling.
• Depression (feeling sad).
• Headache.
• Mild skin rash or itching.
• Nausea or mild vomiting, loss of appetite.
• Warmth or redness in your face, neck, arms, or upper chest.

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088