When This Medicine Should Not Be Used:
You should not use this medicine if you have asthma or severe lung disease. You should not use if you have had an allergic reaction to levobunolol, preservatives such as sulfites, or other beta blocker medicines such as timolol or betaxolol.

How to Use This Medicine:
Drop

• Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. This medicine is not for long-term use.
• Wash your hands before and after using the medicine.
• Shake the eye drops well just before each use.
• Lie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.
• To use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.
• When you use your eye drops with a compliance cap (C cap) for the first time, make sure the number 1 or correct day of the week appears in the window of the cap. After every use, hold the cap and turn the bottle until the cap clicks to the position for your next dose.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your eye doctor knows if you are taking other beta blocker medicines (such as Inderal®, Lopressor®, or Tenormin®) or other high blood pressure medicines.

Warnings While Using This Medicine:

• Check with your doctor before using this medicine if you have emphysema, asthma, bronchitis, heart disease, overactive thyroid, or diabetes.
• This medicine may decrease or increase the level of sugar in blood and cover up symptoms of very low blood sugar (hypoglycemia).
• Talk with your doctor before use if you are pregnant or breastfeeding.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Severe eye irritation or redness
• Slow or irregular heartbeat
• Chest pain
• Wheezing or trouble breathing
• Skin rash, severe itching or hives
• Swelling of legs or ankles
• Hallucinations
• Fever or sore throat

If you notice these less serious side effects, talk with your doctor:

• Stinging or burning of the eye(s)
• Redness, itching or watery eye(s)
• Eye(s) sensitive to light
• Dizziness, drowsiness, or confusion
• Trouble sleeping or abnormal dreams
• Problems having sex
• Nausea
• Nervousness
• Cold hands and feet

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088