When This Medicine Should Not Be Used:
You should not use this medicine if you have had an allergic reaction to fluoride. Do not use on a child under 6 years old unless your doctor tells you to.

How to Use This Medicine:
Liquid, Gel/Jelly, Paste, Cream, Lozenge

• Your doctor will tell you how much medicine to use. Do not use more than directed.
• Follow the instructions on the medicine label if you are using this medicine without a prescription.
• Do not swallow this medicine. It is for topical use on your teeth only.
• Different forms of this medicine are used in different ways. Make sure you follow your health caregivers instructions. Ask your pharmacist if you have any questions about how to use this medicine.
• To use the gel: Brush your teeth with toothpaste and rinse as usual. Apply a thin layer of gel to your teeth with a toothbrush or mouth tray once a day for at least 1 minute. Spit out the gel. For best results, apply at bedtime and do not eat, drink, or rinse your mouth for 30 minutes.
• To use the cream: Use this medicine instead of your regular toothpaste once a day. Apply a thin layer of cream to your toothbrush and brush for 2 minutes. Spit out the cream. For best results, apply at bedtime and do not eat, drink, or rinse your mouth for 30 minutes.
• Some liquid brands of this medicine must be diluted with water before using. Follow the directions on the package.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breast feeding. Tell your doctor if you are allergic to any foods, preservatives, or dyes.
• Too much fluoride can cause white patches or stains on your teeth. If this happens, stop using the medicine and call your doctor.
• If this medicine is being used by a child, an adult should watch the child and make sure they do not swallow the medicine. If they swallow too much of the medicine, it can cause fluoride toxicity. Ask your health caregiver if you have questions or concerns about this.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Burning in your mouth, sore tongue.
• Nausea, vomiting, or diarrhea.
• Vomiting blood.

If you notice these less serious side effects, talk with your doctor:

• Drooling or more saliva than usual.
• Stomach cramps.

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088