When This Medicine Should Not Be Used:
This medicine is not right for everyone. Do not use it if you had an allergic reaction to pimecrolimus.

How to Use This Medicine:
Cream

• Your doctor will tell you how much medicine to use. Do not use more than directed.
• Use this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.
• Wash your hands with soap and water before and after you apply this medicine, unless you are treating your hands.
• Apply a thin layer of the medicine to the affected area. Rub it in gently.
• Do not cover the treated area with a bandage unless directed by your doctor.
• Make sure your skin is completely dry before you apply this medicine. Do not bathe or swim right after you use this medicine. If your doctor recommends a moisturizer, put it on it after this medicine.
• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
• Missed dose: Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have other skin problems (including Netherton syndrome) or a weak immune system.
• This medicine may cause the following problems:
  
  • Virus infections, such as chicken pox, shingles, cold sores, or warts
• A few people who have used this medicine have developed cancer of the lymph glands or skin. It is not known if this medicine caused the cancer.
• This medicine should not be used every day for a long period of time. Stop using it when your eczema gets better. Ask your doctor what to do if the eczema comes back.
• Do not use this medicine to treat a skin problem your doctor has not examined.
• Call your doctor if your symptoms do not improve or if they get worse.
• This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds. Do not receive light therapy (phototherapy) during treatment.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Skin infection or severe skin redness, swelling, or burning
• Swollen, painful, or tender glands in your neck, armpit, or groin

If you notice these less serious side effects, talk with your doctor:

• Mild burning, warmth, itching, or soreness when you apply the cream
• Runny or stuffy nose, cough, sore throat

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088