When This Medicine Should Not Be Used:
You should not receive this medicine if you have had an allergic reaction to tromethamine. You should not receive this medicine if you have kidney failure or if you are not able to urinate. Your child should not receive this medicine if your child has a lung disease or had an aspirin overdose.

How to Use This Medicine:
Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
• A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breast feeding.
• Make sure your doctor knows if you have lung disease, kidney disease, or diabetes.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Chest pain, shortness of breath, or coughing up blood.
• Dark-colored urine or pale stools.
• Fever.
• Nausea, vomiting, loss of appetite, or pain in your upper stomach.
• Pain in your lower leg (calf).
• Shallow breathing.
• Swelling in your hands, ankles, or feet.
• Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

• Pain, itching, burning, swelling, or a lump under your skin where the needle is placed.

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088