When This Medicine Should Not Be Used:
You should not use this medicine if you have had an allergic reaction to zanamivir, lactose, or milk proteins.

How to Use This Medicine:
Disk

• Your doctor will tell you how much medicine to use. Do not use more than directed.
• Start using this medicine as soon as possible after flu symptoms begin or after you are exposed to the flu (within the first 2 days).
• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
• Relenza® is a powder that is used with its own inhaler device called a Diskhaler®. Individual doses of the powder are held in a foil blister pack called a Rotadisk®. Each Rotadisk® is placed into the Diskhaler®. The Diskhaler® pierces 1 blister at a time to load the correct dose when you are ready to use the medicine. An adult needs to watch closely while a child uses the Diskhaler®.
• Do not use this medicine with a nebulizer. It should only be used with the Diskhaler® device that is included in the package.
• Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you plan to get the nasal flu vaccine (FluMist®). You should not receive the vaccine within 2 weeks before or 48 hours after you use this medicine.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breastfeeding or if you have heart disease, lung disease (such as asthma or COPD), or a history of seizures or mental illness.
• This medicine does not take the place of a yearly flu shot. It will not keep you from getting a bacterial infection that causes flu-like symptoms.
• This medicine may cause bronchospasm in people with lung disease (such as asthma or COPD). Stop using this medicine and call your doctor right away if you have trouble breathing, wheezing, or tightness in your chest after you use this medicine.
• This medicine may cause changes in behavior. Tell your doctor if you have trouble sleeping, get upset easily, or have any unusual thoughts or behaviors. Also tell your doctor if you feel nervous, angry, restless, violent, or scared.
• Do not use this medicine to treat other types of flu. Other people can still catch the flu from you even though you feel better while you use this medicine.
• If you also use an asthma medicine that you inhale (such as albuterol, Atrovent®, Combivent®, or Serevent®), use it before you use zanamivir.
• Call your doctor if your symptoms do not improve or if they get worse.
• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Confusion, anxiety, or changes in mood or behavior
• Seeing, hearing, or feeling things that are not there
• Seizures
• Trouble breathing, wheezing, cough, or tightness in your chest

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088