When This Medicine Should Not Be Used:
You should not receive this medicine if you have had an allergic reaction to human antithrombin III.

How to Use This Medicine:
Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
• A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Tell your doctor if you are using heparin.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breast feeding.
• This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines make of human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and testing during manufacture of these medicines. Although the risk is low, talk with you doctor if you have concerns.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Fever, chills.
• Light headedness, fainting, or dizziness.
• Tight feeling in your chest, chest pain, or trouble breathing.

If you notice these less serious side effects, talk with your doctor:

• Muscle cramps.
• Nausea, or bad taste in your mouth.
• Pain, itching, bleeding, or swelling under your skin where the needle is placed.

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088