When This Medicine Should Not Be Used:
You should not use this medicine if you have ever had an allergic reaction to theophylline or related drugs, such as caffeine, aminophylline, dyphylline, oxtriphylline, or theobromine.

How to Use This Medicine:
Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
• A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• There are many other medicines that you should not use while you are using theophylline. Make sure your doctor knows about all other medicines you are using.
• Avoid drinking large amounts of caffeine (such as in coffee, tea, or some soft drinks).

Warnings While Using This Medicine:

• Make sure your doctor knows if you have a history of thyroid problems, heart disease, liver disease, stomach ulcers, cystic fibrosis, or seizures.
• Tell your doctor if you are pregnant or breast feeding.
• Make sure your doctor knows if you are allergic to corn or corn products.
• Make sure your doctor knows if you smoke, or if someone in your family smokes.
• Tell your doctor if you drink alcohol.
• Call your doctor if you develop the flu or a fever while using this medicine. Your doctor may need to change the amount (dose) of medicine that you are using.
• Ask your doctor before you start or stop using any other medicine.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Chest pain or uneven heartbeat.
• Severe nausea or vomiting.
• Redness, pain, or swelling where the IV is given.

If you notice these less serious side effects, talk with your doctor:

• Diarrhea.
• Dry mouth or increased thirst.
• Headache.
• Increase in how much or how often you urinate.
• Irritability, restlessness, or trouble sleeping.

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088