Adenosine deaminase measurement, pleural fluid

This test measures the amount of an enzyme called adenosine deaminase in pleural fluid. It is used when a pleural effusion (build-up of fluid around the lung) caused by tuberculosis is suspected.

Laboratory tests may be done for many reasons. Tests are performed for routine health screenings or if a disease or toxicity is suspected. Lab tests may be used to determine if a medical condition is improving or worsening. Lab tests may also be used to measure the success or failure of a medication or treatment plan. Lab tests may be ordered for professional or legal reasons. You may need this test if you have:

• TB

A thoracentesis is a procedure that requires written consent. Review the consent form with the healthcare worker and ask any questions that you have before signing the consent form. Tell the healthcare worker if you have a medical condition or are using a medication or supplement that causes excessive bleeding. You should also report if you have a history of allergic or other reactions to local anesthetics. You may need to have blood tests and a chest x-ray performed before the thoracentesis.

Pleural fluid is the fluid in between the membrane linings of your lungs. A procedure called a thoracentesis is done to get a pleural fluid sample for testing. A healthcare worker will first need to locate the fluid that needs to be sampled. This is done by a chest x-ray, ultrasound, or by percussion (rhythmically pounding the chest wall). Once the fluid is located, a healthcare worker may hold up the arm on the same side where the procedure will be done. Your skin will be cleaned with antiseptic, and a local anesthetic is injected to numb the area. A needle will be inserted into the fluid pocket. Fluid samples are then drawn out using a needle attached to a syringe. When a large enough sample is collected, the needle will be removed. A thoracentesis may be done with or without the assistance of ultrasound or CT scan.

The amount of discomfort you feel will depend on many factors, including your sensitivity to pain. Communicate how you are feeling with the person doing the procedure. Inform the person doing the procedure if you feel that you cannot continue with the procedure.

Before a thoracentesis, a local anesthetic is given to the procedure site to numb the area. You may feel mild discomfort or stinging when the numbing medicine is injected. You may still be able to feel pressure or discomfort during the procedure. Your procedure site may be sore for several days.

After a thoracentesis, a bandage will be secured over your procedure site and pressure held until the bleeding or fluid leakage stops. You may receive a chest x-ray to check for complications. The chest x-ray may be repeated to look for the return of fluid in the lung. Follow your healthcare worker’s instructions for changing your bandage and other wound care. Tell your healthcare worker immediately if you have a new onset of difficulty breathing, shortness of breath, chest pain, weakness, fatigue, fever, or dizziness. Also immediately tell your healthcare worker if you have increased bleeding or drainage from the procedure site.

You have the right to help plan your care. To help with this plan, you must learn about your health condition and how it may be treated. You can then discuss treatment options with your caregivers. Work with them to decide what care may be used to treat you. You always have the right to refuse treatment.