When This Medicine Should Not Be Used:
You should not use this medicine if you have had an allergic reaction to other hormonal infertility treatments. You might not be able to use this medicine if you have thyroid problems, adrenal gland problems, or certain types of tumors. Women should not use this medicine if they have any unusual vaginal bleeding, have had any unusual growth in the ovaries, or if they are pregnant or breast feeding.

How to Use This Medicine:
Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
• You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
• You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
• Gonal-f™ RFF comes in a prefilled syringe. No mixing or measuring of the medicine is necessary.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• Using this medicine if you are already pregnant can harm your unborn baby.
• Make sure your doctor knows if you have liver disease, heart disease, or a history of breathing problems such as asthma. Make sure your doctor knows if you have ever had a stroke, or problems with blood clots.
• This medicine may cause you to become pregnant with more than one baby (twins, triplets, or more).
• Along with using this medicine, you will need to visit your doctor for regular tests and procedures. It may take several months for you to become pregnant.

Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Breakthrough vaginal bleeding.
• Chest pain, shortness of breath, or coughing up blood.
• Dark-colored urine or pale stools.
• Decrease in how much or how often you urinate.
• Fever, chills, cough, runny or stuffy nose, body aches, or sore throat.
• Pain in your lower leg (calf).
• Pain or swelling in your lower abdomen.
• Painful or difficult breathing.
• Rapid weight gain.
• Vomiting, stomach pain, or diarrhea.
• Yellowing of your skin or the whites of your eyes.

If you notice these less serious side effects, talk with your doctor:

• Acne.
• Breast pain or enlargement.
• Headache or fatigue.
• Nausea.
• Pain or swelling where the shot is given.

If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088